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Last updated: 2017/1/22
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EIF2S1 polyclonal antibody

  • Catalog # : PAB5339
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of EIF2S1.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding S51 of human EIF2S1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:100)
    Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from A-431 cells, untreated or EGF-treated (200 ng/ml, 5 min), using EIF2S1 polyclonal antibody (Cat # PAB5339) .
  • Immunohistochemistry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 1965
  • Gene Name:
  • EIF2S1
  • Gene Alias:
  • EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A
  • Gene Description:
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • Gene Summary:
  • The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM
  • Other Designations:
  • eIF-2-alpha,eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD )
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