Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDX1 polyclonal antibody (Cat # PAB4713) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq
caudal type homeo box transcription factor 1,caudal type homeobox transcription factor 1,caudal-type homeobox protein CDX1