Western blot analysis of SRPK1 polyclonal antibody (Cat # PAB4560) in mouse brain tissue lysate (35 ug/lane). SRPK1 (arrow) was detected using the purified SRPK1 polyclonal antibody (Cat # PAB4560) (1 : 60 dilution).
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined. [provided by RefSeq