The RPS6KA4 polyclonal antibody (Cat # PAB4524) is used in Western blot to detect RPS6KA4 in placenta tissue lysate .
Indirect immunofluorescence analysis showed that RPS6KA4 is predominantly localized in the nucleus of parental (10T1/2) and oncogene-transformed (Ciras-3) mouse fibroblasts . Cells were co-stained with DAPI to visualize nucleus compartment . Data is kindly provided by B . Drobic and Dr . J . Davie from University of Manitoba (Winnipeg, Canada) .
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
mitogen- and stress-activated protein kinase 2,ribosomal protein S6 kinase alpha 4,ribosomal protein S6 kinase, 90kD, polypeptide 4,ribosomal protein kinase B