TYRO3 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of TYRO3 polyclonal antibody (Cat # PAB3391) in mouse brain lysate. SKY (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with TYRO3 polyclonal antibody (Cat # PAB3391) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TYRO3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human TYRO3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TYRO3 polyclonal antibody (Cat # PAB3391) in mouse brain lysate. SKY (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with TYRO3 polyclonal antibody (Cat # PAB3391) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. -
Gene Info — TYRO3
Entrez GeneID
7301Protein Accession#
NP_006284Gene Name
TYRO3
Gene Alias
BYK, Brt, Dtk, FLJ16467, RSE, Sky, Tif
Gene Description
TYRO3 protein tyrosine kinase
Omim ID
600341Gene Ontology
HyperlinkOther Designations
Tyro3 protein tyrosine kinase (sea-related receptor tyrosine kinase)|tyrosine-protein kinase receptor TYRO3
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Interactome
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Disease
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Publication Reference
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Prognostic Significance of TYRO3 Receptor Tyrosine Kinase Expression in Gastric Cancer.
Chihiro Uejima, Masaki Morimoto, Manabu Yamamoto, Kazushi Hara, Wataru Miyauchi, Ken Sugezawa, Yoichiro Tada, Akimitsu Tanio, Kyoichi Kihara, Tomoyuki Matsunaga, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Yoshihisa Umekita, Yoshiyuki Fujiwara.
Anticancer Research 2020 Oct; 40(10):5593.
Application：IHC-P, Human, Human gastric cancer, Human pancreas.
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Regional localization of human chromosome 15 loci.
Richard I, Broux O, Chiannilkulchai N, Fougerousse F, Allamand V, Bourg N, Brenguier L, Devaud C, Pasturaud P, Roudaut C, et al..
Genomics 1994 Oct; 23(3):619.
Application：WB-Ce, WB-Tr, Human, Mammalian cells.
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rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain.
Mark MR, Scadden DT, Wang Z, Gu Q, Goddard A, Godowski PJ.
The Journal of Biological Chemistry 1994 Apr; 269(14):10720.
Application：IP, WB-Tr, Mouse, NIH/3T3 cells.
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Prognostic Significance of TYRO3 Receptor Tyrosine Kinase Expression in Gastric Cancer.
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