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Last updated: 2016/12/4
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PDGFRL polyclonal antibody

  • Catalog # : PAB3378
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PDGFRL.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PDGFRL.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysate (35 ug/lane) with PDGFRL polyclonal antibody (Cat # PAB3378).
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of PDGFRL (arrow) using PDGFRL polyclonal antibody (Cat # PAB3378).
    293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDGFRL gene (Lane 2).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human cancer tissue reacted with PDGFRL polyclonal antibody (Cat # PAB3378) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5157
  • Gene Name:
  • PDGFRL
  • Gene Alias:
  • PDGRL,PRLTS
  • Gene Description:
  • platelet-derived growth factor receptor-like
  • Gene Summary:
  • This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161390,platelet-derived growth factor receptor-like protein,platelet-derived growth factor-beta-like tumor suppressor
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