Rabbit polyclonal antibody raised against partial recombinant human ACE2.
Immunogen:
Recombinant protein corresponding to residues at internal region of human ACE2.
Host:
Rabbit
Reactivity:
Human
Specificity:
This antibody detects endogenous levels of total ACE2 protein.
Form:
Liquid
Purification:
Antigen affinity purification
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:25-1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:25-1:100) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH7.3 (50% Glycerol, 0.05% sodium azide).
Storage Instruction:
Store at -20°C is stable for one year. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq
Other Designations:
ACE-related carboxypeptidase,OTTHUMP00000022963,angiotensin I converting enzyme 2,angiotensin converting enzyme-like protein