ACE2 monoclonal antibody, clone AC18F
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More Files
- More Functions
Western Blot
Western Blot of ACE2 monoclonal antibody, clone AC18F at 1:2000 dilution. Lane 1: hACE2 (Fc protein). Lane 2: hACE2 (Ecto domain) (FLAG-Tag) . Lane 3: Other hGITR (Fc protein) (control).
Flow Cytometry
The HepG2 cell line is treated with CellTase solution before analysis and then stained with ACE2 monoclonal antibody, clone AC18F (pink line) (Cat# MAB16024) or an isotype control, mouse IgG1 (green line) at 1 ug/106 cell each, revealed with a PE-conjugated goat anti-mouse IgG and then analyzed to flow cytometry.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human ACE2.
Immunogen
Recombinant protein corresponding to human ACE2.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
ELISA (1:2000-10000)
Flow Cytometry (1:1000)
Western Blot (1:2000-10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4.
Storage Instruction
For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western Blot of ACE2 monoclonal antibody, clone AC18F at 1:2000 dilution. Lane 1: hACE2 (Fc protein). Lane 2: hACE2 (Ecto domain) (FLAG-Tag) . Lane 3: Other hGITR (Fc protein) (control).Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
The HepG2 cell line is treated with CellTase solution before analysis and then stained with ACE2 monoclonal antibody, clone AC18F (pink line) (Cat# MAB16024) or an isotype control, mouse IgG1 (green line) at 1 ug/106 cell each, revealed with a PE-conjugated goat anti-mouse IgG and then analyzed to flow cytometry. -
Gene Info — ACE2
Entrez GeneID
59272Protein Accession#
NP_068576Gene Name
ACE2
Gene Alias
ACEH, DKFZp434A014
Gene Description
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Omim ID
300335Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq
Other Designations
ACE-related carboxypeptidase|OTTHUMP00000022963|angiotensin I converting enzyme 2|angiotensin converting enzyme-like protein
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Interactome
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Pathway
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Disease
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