ARID3B polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human testis tissue reacted with ARID3B polyclonal antibody (Cat # PAB3144) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ARID3B.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ARID3B.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human testis tissue reacted with ARID3B polyclonal antibody (Cat # PAB3144) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. -
Gene Info — ARID3B
Entrez GeneID
10620Protein Accession#
NP_006456;Q8IVW6Gene Name
ARID3B
Gene Alias
BDP, DRIL2
Gene Description
AT rich interactive domain 3B (BRIGHT-like)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq
Other Designations
AT rich interactive domain 3B|AT rich interactive domain 3B (BRIGHT- like)|bright and dead ringer
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Interactome
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Disease
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Publication Reference
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ARID proteins come in from the desert.
Kortschak RD, Tucker PW, Saint R.
Trends in Biochemical Sciences 2000 Jun; 25(6):294.
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Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product.
Numata S, Claudio PP, Dean C, Giordano A, Croce CM.
Cancer Research 1999 Aug; 59(15):3741.
Application：Func, WB-Ce, Human, K-562 cells, Recombinant protein.
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ARID proteins come in from the desert.
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