ARID3B mouse monoclonal antibody (hybridoma)
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant ARID3B.
Immunogen
ARID3B (AAH60824.1, 1 a.a. ~ 253 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEPLQQQQQQQQQQQKQPHLAPLQMDAREKQGQQMREAQFLYAQKLVTQPTLLSATAGRPSGSTPLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDGDDEVAEVAEKETQAASKYFHVQKVARQDPRVAPMSNLLPAPGLPPHGQQAKEDHTKDASKASPSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFVFMQKRGECASTHHSNSGNTDRVPTVC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (78)
Quality Control Testing
Antibody reactivity and specificity confirmed by ELISA and Western Blot.
Deliverables
Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.
Note
Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.
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Applications
Western Blot (Transfected lysate)
Western Blot (Recombinant protein)
ELISA
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Gene Info — ARID3B
Entrez GeneID
10620GeneBank Accession#
BC060824.1Protein Accession#
AAH60824.1Gene Name
ARID3B
Gene Alias
BDP, DRIL2
Gene Description
AT rich interactive domain 3B (BRIGHT-like)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq
Other Designations
AT rich interactive domain 3B|AT rich interactive domain 3B (BRIGHT- like)|bright and dead ringer
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Interactome
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Disease
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Publication Reference
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Arid3b Is Critical for B Lymphocyte Development.
Kurkewich JL, Klopfenstein N, Hallas WM, Wood C, Sattler RA, Das C, Tucker H, Dahl R, Cowden Dahl KD.
PLoS One 2016 Aug; 11(8):e0161468.
Application：EMSA, CO-IP, Mouse, Bcl1 B cell lymphoma cells.
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Arid3b Is Critical for B Lymphocyte Development.
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