PDPN polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of EFO-21 cell lysate with PDPN polyclonal antibody (Cat # PAB31389).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gall bladder with PDPN polyclonal antibody (Cat # PAB31389) shows distinct positivity in lymphatic vessels.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PDPN.
Immunogen
Recombinant protein corresponding to human PDPN.
Sequence
RLPRVWEARAPSLSGAPAPTPPAPPPSRSSRLGLWPRCFLIFPQLRILLLGPQESNNSTGTMWKVSALLFVLGSASLWVLAEGASTGQPEDDTETTGLEGGVAMPGAEDDVVTPGTSEDRYKSGLTTLVATSVNS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of EFO-21 cell lysate with PDPN polyclonal antibody (Cat # PAB31389).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gall bladder with PDPN polyclonal antibody (Cat # PAB31389) shows distinct positivity in lymphatic vessels. -
Gene Info — PDPN
Entrez GeneID
10630Protein Accession#
Q86YL7Gene Name
PDPN
Gene Alias
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2
Gene Description
podoplanin
Omim ID
608863Gene Ontology
HyperlinkGene Summary
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000009640|OTTHUMP00000044504|glycoprotein, 36-KD|hT1alpha-1|hT1alpha-2|lung type I cell membrane associated glycoprotein|lung type-I cell membrane-associated glycoprotein|lung type-I cell membrane-associated glycoprotein (T1A-2)
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Interactome
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Disease
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Publication Reference
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Structural and functional features of central nervous system lymphatic vessels.
Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, Derecki NC, Castle D, Mandell JW, Lee KS, Harris TH, Kipnis J.
Nature 2015 Jul; 523(7560):337.
Application：IF, IHC-Fr, Human, Human brain, Human dura.
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Structural and functional features of central nervous system lymphatic vessels.
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