SPG11 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with SPG11 polyclonal antibody (Cat # PAB31236) shows moderate cytoplasmic and nuclear positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SPG11.
Immunogen
Recombinant protein corresponding to human SPG11.
Sequence
RLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with SPG11 polyclonal antibody (Cat # PAB31236) shows moderate cytoplasmic and nuclear positivity in glandular cells. -
Gene Info — SPG11
Entrez GeneID
80208Protein Accession#
Q96JI7Gene Name
SPG11
Gene Alias
DKFZp762B1512, FLJ21439, KIAA1840, SPATACSIN
Gene Description
spastic paraplegia 11 (autosomal recessive)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Disease
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