STEAP2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with STEAP2 polyclonal antibody (Cat # PAB30999) shows moderate cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human STEAP2.
Immunogen
Recombinant protein corresponding to human STEAP2.
Sequence
EYLASLFPDSLIVKGFNVVSAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPIDLGSLSSAREIE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with STEAP2 polyclonal antibody (Cat # PAB30999) shows moderate cytoplasmic positivity in glandular cells. -
Gene Info — STEAP2
Entrez GeneID
261729Protein Accession#
Q8NFT2Gene Name
STEAP2
Gene Alias
IPCA1, PCANAP1, PUMPCn, STAMP1, STMP
Gene Description
six transmembrane epithelial antigen of the prostate 2
Omim ID
605094Gene Ontology
HyperlinkGene Summary
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000067572|OTTHUMP00000067575|SixTransMembrane Protein of Prostate 1|prostate cancer associated protein 1|protein upregulated in metastatic prostate cancer|six transmembrane epithelial antigen of prostate 2
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Interactome
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Disease
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