FDFT1 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western Blot analysis of human cell line RT-4 with FDFT1 polyclonal antibody (Cat # PAB30565).
Western Blot (Cell lysate)
Western Blot analysis with FDFT1 polyclonal antibody (Cat # PAB30565).
Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human adrenal gland with FDFT1 polyclonal antibody (Cat # PAB30565) shows strong cytoplasmic positivity in cortical cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with FDFT1 polyclonal antibody (Cat # PAB30565) shows positivity in endoplasmic reticulum. Antibody staining is shown in green.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human FDFT1.
Immunogen
Recombinant protein corresponding to amino acids 10-148 of human FDFT1.
Sequence
PEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICR
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1 - 4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50 - 1:200)
Western Blot (1:100 - 1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of human cell line RT-4 with FDFT1 polyclonal antibody (Cat # PAB30565).Western Blot (Cell lysate)
Western Blot analysis with FDFT1 polyclonal antibody (Cat # PAB30565).
Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human adrenal gland with FDFT1 polyclonal antibody (Cat # PAB30565) shows strong cytoplasmic positivity in cortical cells.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with FDFT1 polyclonal antibody (Cat # PAB30565) shows positivity in endoplasmic reticulum. Antibody staining is shown in green. -
Gene Info — FDFT1
Entrez GeneID
2222Protein Accession#
P37268Gene Name
FDFT1
Gene Alias
DGPT, ERG9, SQS, SS
Gene Description
farnesyl-diphosphate farnesyltransferase 1
Omim ID
184420Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq
Other Designations
FPP:FPP farnesyltransferase|presqualene-di-diphosphate synthase|squalene synthase
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Interactome
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Pathway
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Disease
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