Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gallbladder with GRK6 polyclonal antibody (Cat # PAB30495) shows dot like cytoplasmic positivity in glandular cells at 1:50-1:200 dilution.
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq