STAB1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human esophagus with STAB1 polyclonal antibody (Cat # PAB30389) shows strong cytoplasmic positivity in squamous epithelial cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human STAB1.
Immunogen
Recombinant protein corresponding to human STAB1.
Sequence
LEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILH
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human esophagus with STAB1 polyclonal antibody (Cat # PAB30389) shows strong cytoplasmic positivity in squamous epithelial cells at 1:200-1:500 dilution. -
Gene Info — STAB1
Entrez GeneID
23166Protein Accession#
Q9NY15Gene Name
STAB1
Gene Alias
CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, STAB-1
Gene Description
stabilin 1
Omim ID
608560Gene Ontology
HyperlinkGene Summary
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq
Other Designations
MS-1 antigen|common lymphatic endothelial and vascular endothelial receptor-1|fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1
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Interactome
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Disease
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