KCNQ2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with KCNQ2 polyclonal antibody (Cat # PAB29886).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with KCNQ2 polyclonal antibody (Cat # PAB29886).
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Specification
Product Description
Rabbit polyclonal antibody raised against partial synthetic protein of human KCNQ2.
Immunogen
A synthetic peptide corresponding to amino acids 189-238 of human KCNQ2.
Sequence
GNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI
Host
Rabbit
Theoretical MW (kDa)
43
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:250)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1X PBS , pH 7.4 (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C for up to one week. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with KCNQ2 polyclonal antibody (Cat # PAB29886).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with KCNQ2 polyclonal antibody (Cat # PAB29886). -
Gene Info — KCNQ2
Entrez GeneID
3785Protein Accession#
Q5VYU0Gene Name
KCNQ2
Gene Alias
BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1
Gene Description
potassium voltage-gated channel, KQT-like subfamily, member 2
Gene Ontology
HyperlinkGene Summary
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq
Other Designations
neuroblastoma-specific potassium channel protein|potassium voltage-gated channel KQT-like protein 2
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Interactome
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Disease
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