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KCNQ2 polyclonal antibody

  • Catalog # : PAB29886
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial synthetic protein of human KCNQ2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 189-238 of human KCNQ2.
  • Sequence:
  • GNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 43
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:250)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1X PBS , pH 7.4 (2% sucrose, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C for up to one week. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HepG2 cell lysate with KCNQ2 polyclonal antibody (Cat # PAB29886).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with KCNQ2 polyclonal antibody (Cat # PAB29886).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3785
  • Gene Name:
  • KCNQ2
  • Gene Alias:
  • BFNC,EBN,EBN1,ENB1,HNSPC,KCNA11,KV7.2,KVEBN1
  • Gene Description:
  • potassium voltage-gated channel, KQT-like subfamily, member 2
  • Gene Summary:
  • The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • neuroblastoma-specific potassium channel protein,potassium voltage-gated channel KQT-like protein 2
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