KCNQ2 DNAxPab
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of KCNQ2 expression in transfected 293T cell line by KCNQ2 DNAxPab polyclonal antibody.
Lane 1: KCNQ2 transfected lysate(31.13 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human KCNQ2 DNA using DNAx™ Immune technology.
Technology
Immunogen
KCNQ2 (NP_742107.1, 1 a.a. ~ 91 a.a.) partial-length human DNA
Sequence
MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGW
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KCNQ2 expression in transfected 293T cell line by KCNQ2 DNAxPab polyclonal antibody.
Lane 1: KCNQ2 transfected lysate(31.13 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — KCNQ2
Entrez GeneID
3785GeneBank Accession#
NM_172109.1Protein Accession#
NP_742107.1Gene Name
KCNQ2
Gene Alias
BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1
Gene Description
potassium voltage-gated channel, KQT-like subfamily, member 2
Gene Ontology
HyperlinkGene Summary
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq
Other Designations
neuroblastoma-specific potassium channel protein|potassium voltage-gated channel KQT-like protein 2
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Interactome
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Disease
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