SH3KBP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) with SH3KBP1 polyclonal antibody (Cat # PAB29542).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with SH3KBP1 polyclonal antibody (Cat # PAB29542) shows strong cytoplasmic positivity.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human SH3KBP1.
Immunogen
Recombinant protein corresponding to human SH3KBP1.
Sequence
WEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSSLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDY
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) with SH3KBP1 polyclonal antibody (Cat # PAB29542).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with SH3KBP1 polyclonal antibody (Cat # PAB29542) shows strong cytoplasmic positivity. -
Gene Info — SH3KBP1
Entrez GeneID
30011Gene Name
SH3KBP1
Gene Alias
CIN85, GIG10, MIG18
Gene Description
SH3-domain kinase binding protein 1
Omim ID
300374Gene Ontology
HyperlinkGene Summary
CBL (MIM 165360) constitutively interacts with SH3 domain-containing proteins and, upon tyrosine phosphorylation, with SH2 domain-containing proteins. The SH3KBP1 gene encodes an 85-kD CBL-interacting protein that enhances tumor necrosis factor (MIM 191160)-mediated apoptotic cell death (Narita et al., 2001 [PubMed 11474197]).[supplied by OMIM
Other Designations
OTTHUMP00000023022|OTTHUMP00000023024|OTTHUMP00000061480|c-Cbl-interacting protein|migration-inducing gene 18 protein
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Interactome
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Pathway
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