IRAK1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human IRAK1.
Immunogen
Recombinant protein corresponding to human IRAK1.
Sequence
GAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with IRAK1 polyclonal antibody (Cat # PAB29458) shows strong cytoplasmic positivity in exocrine glands.Immunofluorescence
Immunofluorescent staining of human cell line MCF7 with IRAK1 polyclonal antibody (Cat # PAB29458) at 1-4 ug/mL concentration shows positivity in nucleus and cytoplasm. -
Gene Info — IRAK1
Entrez GeneID
3654Gene Name
IRAK1
Gene Alias
IRAK, pelle
Gene Description
interleukin-1 receptor-associated kinase 1
Omim ID
300283Gene Ontology
HyperlinkGene Summary
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000026014|OTTHUMP00000026020|Pelle homolog
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Interactome
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