KPNA5 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with KPNA5 polyclonal antibody (Cat # PAB29455) shows strong nuclear positivity in cells in seminiferus ducts.
Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with KPNA5 polyclonal antibody (Cat # PAB29455) at 1-4 ug/mL concentration shows positivity in cytoplasm.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human KPNA5.
Immunogen
Recombinant protein corresponding to human KPNA5.
Sequence
KRRNVYLPRNDESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with KPNA5 polyclonal antibody (Cat # PAB29455) shows strong nuclear positivity in cells in seminiferus ducts.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with KPNA5 polyclonal antibody (Cat # PAB29455) at 1-4 ug/mL concentration shows positivity in cytoplasm. -
Gene Info — KPNA5
Entrez GeneID
3841Gene Name
KPNA5
Gene Alias
IPOA6, SRP6
Gene Description
karyopherin alpha 5 (importin alpha 6)
Omim ID
604545Gene Ontology
HyperlinkGene Summary
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. [provided by RefSeq
Other Designations
OTTHUMP00000017076|importin alpha 6|karyopherin alpha 5
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