SP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human SP2.
Immunogen
Recombinant protein corresponding to human SP2.
Sequence
KLVPIKPAPLPLSPGKNSFGILSSKGNILQIQGSQLSASYPGGQLVFAIQNPTMINKGTRSNANIQYQAVPQIQASNSQTIQVQPNLTNQIQIIPGTNQAIITPSPSSHKPVPIKPAPIQKSST
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human tonsil with SP2 polyclonal antibody (Cat # PAB29400) shows strong nuclear positivity in lymphoid cells outside reaction center.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SP2 polyclonal antibody (Cat # PAB29400) at 1-4 ug/mL concentration shows positivity in nucleus. -
Gene Info — SP2
Entrez GeneID
6668Gene Name
SP2
Gene Alias
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Gene Description
Sp2 transcription factor
Omim ID
601801Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq
Other Designations
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Interactome
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