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GRIN1 (phospho S890) polyclonal antibody

  • Catalog # : PAB29269
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GRIN1.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S890 of human GRIN1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 120
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • GRIN1 (phospho S890) polyclonal antibody detects endogenous levels of human GRIN1 only when phosphorylated at serine 890.
  • Form:
  • Liquid
  • Purification:
  • Affinity Chromatography
  • Recommend Usage:
  • Immunofluorescence (1:100~1:200)
    Immunohistochemistry (1:50~1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain tissue with GRIN1 (phospho S890) polyclonal antibody (Cat# PAB29269) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of methanol-fixed A-549 cells with GRIN1 (phospho S890) polyclonal antibody (Cat# PAB29269) without blocking peptide (A) or preincubated with blocking peptide (B) at 1:100-1:200 dilution.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 2902
  • Gene Name:
  • GRIN1
  • Gene Alias:
  • NMDA1,NMDAR1,NR1
  • Gene Description:
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Gene Summary:
  • The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq
  • Other Designations:
  • N-methyl-D-aspartate receptor channel, subunit zeta-1,NMDA receptor 1,OTTHUMP00000022678,glutamate [NMDA] receptor subunit zeta 1
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