Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer tissue with ITGB1 (phospho T789) polyclonal antibody (Cat# PAB29262) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq