Chicken polyclonal antibody raised against recombinant Human MAPT.
Two different KLH-conjugated synthetic peptides corresponding to different regions of the MAPT sequences, shared between the mouse and human proteins, and did not contain any of the serine and threonine residues known to undergo phosphorylation.
Antigen affinity purification
Quality Control Testing:
MAPT polyclonal antibody (Cat # PAB29092) was analyzed by immunohistochemical staining (at a dilution of 1:1000). Neuron cells with positive staining in the hippocampus of a patient with Alzheimer's desease.
Immunocytochemistry(1:1000-1:2000) Immunohistochemistry(1:1000-1:2000) Western Blot The optimal working dilution should be determined by the end user.
In PBS, pH 7.2 (0.02% sodium azide)
Store at 4°C and avoid from light. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
G protein beta1/gamma2 subunit-interacting factor 1,microtubule-associated protein tau, isoform 4