MAPT (phospho T231) recombinant monoclonal antibody, clone 1G9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MAPT.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding T231 of human MAPT.
Theoretical MW (kDa)
Calculated MW: 46 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysate (not treated) and Lane 2: Hela whole cell lysate (treated with Calyculin A 100 nM/60 mins) with MAPT (phospho T231) recombinant monoclonal antibody, clone 1G9 (Cat # RAB04247).Enzyme-linked Immunoabsorbent Assay
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Gene Info — MAPT
Entrez GeneID
4137Protein Accession#
P10636Gene Name
MAPT
Gene Alias
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Gene Description
microtubule-associated protein tau
Gene Ontology
HyperlinkGene Summary
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
Other Designations
G protein beta1/gamma2 subunit-interacting factor 1|microtubule-associated protein tau, isoform 4
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