PLP1 polyclonal antibody
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More Files
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PLP1 polyclonal antibody (Cat # PAB29088) was analyzed by immunocytological staining (at a dilution of 1:2000).
In this tissue section through an e13 mouse brain, PLP1 (green) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.
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Specification
Product Description
Chicken polyclonal antibody raised against recombinant Human PLP1.
Immunogen
A KLH-conjugated synthetic peptide corresponding to human and mouse PLP1.(NP_000524, NP_955772, P60202)
Host
Chicken
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgY
Quality Control Testing
Immunocytochemistry
PLP1 polyclonal antibody (Cat # PAB29088) was analyzed by immunocytological staining (at a dilution of 1:2000).
In this tissue section through an e13 mouse brain, PLP1 (green) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.Recommend Usage
Immunocytochemistry(1:1000-1:2000)
Immunohistochemistry(1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.02% sodium azide)
Storage Instruction
Store at 4°C and avoid from light. For long term storage, dilute the antibody with sterile glycerol and store it at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunocytochemistry
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Gene Info — PLP1
Entrez GeneID
5354Protein Accession#
NP_000524Gene Name
PLP1
Gene Alias
HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
Gene Description
proteolipid protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023761|OTTHUMP00000023762|lipophilin|major myelin proteolipid protein
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Gene Info — Plp1
Entrez GeneID
18823Protein Accession#
NP_000524Gene Name
Plp1
Gene Alias
DM20, Plp, jimpy, jp, msd, rsh
Gene Description
proteolipid protein (myelin) 1
Gene Ontology
HyperlinkOther Designations
OTTMUSP00000017800|myelin proteolipid protein|myelin synthesis deficiency|proteolipid protein 1|rump shaker
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Interactome
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Disease
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