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PLP1 polyclonal antibody

  • Catalog # : PAB29088
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  • Specification
  • Product Description:
  • Chicken polyclonal antibody raised against recombinant Human PLP1.
  • Immunogen:
  • A KLH-conjugated synthetic peptide corresponding to human and mouse PLP1.(NP_000524, NP_955772, P60202)
  • Host:
  • Chicken
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgY
  • Quality Control Testing:
  • Immunocytochemistry

    QC Testing of PAB29088
    PLP1 polyclonal antibody (Cat # PAB29088) was analyzed by immunocytological staining (at a dilution of 1:2000).
    In this tissue section through an e13 mouse brain, PLP1 (green) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.
  • Recommend Usage:
  • Immunocytochemistry(1:1000-1:2000)
    Immunohistochemistry(1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C and avoid from light. For long term storage, dilute the antibody with sterile glycerol and store it at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 5354
  • Gene Name:
  • PLP1
  • Gene Alias:
  • HLD1,MMPL,PLP,PLP/DM20,PMD,SPG2
  • Gene Description:
  • proteolipid protein 1
  • Gene Summary:
  • This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023761,OTTHUMP00000023762,lipophilin,major myelin proteolipid protein
  • Gene Information
  • Gene Name:
  • Plp1
  • Gene Alias:
  • DM20,Plp,jimpy,jp,msd,rsh
  • Gene Description:
  • proteolipid protein (myelin) 1
  • Other Designations:
  • OTTMUSP00000017800,myelin proteolipid protein,myelin synthesis deficiency,proteolipid protein 1,rump shaker
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