TRADD polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Raw 264.7 cell lysate treated with LPS with TRADD polyclonal antibody (Cat # PAB27102) at 1:500 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using TRADD polyclonal antibody (Cat # PAB27102).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TRADD.
Immunogen
A synthetic peptide corresponding to human TRADD.
Host
Rabbit
Theoretical MW (kDa)
~35.0
Reactivity
Human, Mouse
Specificity
TRADD polyclonal antibody detects endogenous levels of TRADD protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Raw 264.7 cell lysate treated with LPS with TRADD polyclonal antibody (Cat # PAB27102) at 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using TRADD polyclonal antibody (Cat # PAB27102). -
Gene Info — TRADD
Entrez GeneID
8717Protein Accession#
Q15628Gene Name
TRADD
Gene Alias
Hs.89862, MGC11078
Gene Description
TNFRSF1A-associated via death domain
Omim ID
603500Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq
Other Designations
TNFR1-associated death domain protein|tumor necrosis factor receptor type 1 associated death domain protein|tumor necrosis factor receptor-1-associated protein
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Interactome
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Pathway
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Disease
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