TRADD purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TRADD protein.
Immunogen
TRADD (NP_003780.1, 1 a.a. ~ 312 a.a) full-length human protein.
Sequence
MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (77)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TRADD MaxPab rabbit polyclonal antibody. Western Blot analysis of TRADD expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of TRADD expression in transfected 293T cell line (H00008717-T01) by TRADD MaxPab polyclonal antibody.
Lane 1: TRADD transfected lysate(34.20 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to TRADD on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — TRADD
Entrez GeneID
8717GeneBank Accession#
NM_003789Protein Accession#
NP_003780.1Gene Name
TRADD
Gene Alias
Hs.89862, MGC11078
Gene Description
TNFRSF1A-associated via death domain
Omim ID
603500Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq
Other Designations
TNFR1-associated death domain protein|tumor necrosis factor receptor type 1 associated death domain protein|tumor necrosis factor receptor-1-associated protein
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Interactome
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Pathway
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Disease
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