SENP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate with SENP1 polyclonal antibody (Cat # PAB27099).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using SENP1 polyclonal antibody (Cat # PAB27099).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SENP1.
Immunogen
A synthetic peptide corresponding to human SENP1.
Host
Rabbit
Theoretical MW (kDa)
73
Reactivity
Human, Mouse
Specificity
SENP1 polyclonal antibody detects endogenous levels of SENP1 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat cell lysate with SENP1 polyclonal antibody (Cat # PAB27099).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using SENP1 polyclonal antibody (Cat # PAB27099). -
Gene Info — SENP1
Entrez GeneID
29843Protein Accession#
Q9P0U3Gene Name
SENP1
Gene Alias
SuPr-2
Gene Description
SUMO1/sentrin specific peptidase 1
Gene Ontology
HyperlinkGene Summary
The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]).[supplied by OMIM
Other Designations
SUMO1/sentrin specific protease 1|sentrin/SUMO-specific protease|sentrin/SUMO-specific protease 1
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