JUP polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of JUP polyclonal antibody (Cat # PAB27027) in extracts from HeLa cells.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of JUP polyclonal antibody (Cat # PAB27027) in paraffin-embedded human breast carcinoma tissue.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of JUP.
Immunogen
A synthetic peptide corresponding to human JUP.
Host
Rabbit
Theoretical MW (kDa)
82
Reactivity
Human, Mouse, Rat
Specificity
JUP polyclonal antibody detects endogenous levels of JUP protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of JUP polyclonal antibody (Cat # PAB27027) in extracts from HeLa cells.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of JUP polyclonal antibody (Cat # PAB27027) in paraffin-embedded human breast carcinoma tissue.Enzyme-linked Immunoabsorbent Assay
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Gene Info — JUP
Entrez GeneID
3728Protein Accession#
P14923Gene Name
JUP
Gene Alias
ARVD12, CTNNG, DP3, DPIII, PDGB, PKGB
Gene Description
junction plakoglobin
Gene Ontology
HyperlinkGene Summary
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq
Other Designations
OTTHUMP00000164735|catenin (cadherin-associated protein), gamma (80kD)|catenin (cadherin-associated protein), gamma 80kDa|gamma-catenin
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Interactome
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Pathway
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Disease
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