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APC polyclonal antibody

  • Catalog # : PAB27020
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of APC.
  • Immunogen:
  • A synthetic peptide corresponding to human APC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 310
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • APC polyclonal antibody detects endogenous levels of APC protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of APC polyclonal antibody (Cat # PAB27020) in extracts from COLO 205 cells.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of APC polyclonal antibody (Cat # PAB27020) in paraffin-embedded human lung carcinoma tissue.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 324
  • Gene Name:
  • APC
  • Gene Alias:
  • BTPS2,DP2,DP2.5,DP3,GS
  • Gene Description:
  • adenomatous polyposis coli
  • Gene Summary:
  • This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq
  • Other Designations:
  • adenomatosis polyposis coli tumor suppressor
  • Interactome
  • Interactome
  • Related Disease
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