ME3 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Raw 264.7 cell lysate with ME3 polyclonal antibody (Cat # PAB27010).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using ME3 polyclonal antibody (Cat # PAB27010).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ME3.
Immunogen
A synthetic peptide corresponding to human ME3.
Host
Rabbit
Theoretical MW (kDa)
67
Reactivity
Human, Mouse
Specificity
ME3 polyclonal antibody detects endogenous levels of ME3 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Raw 264.7 cell lysate with ME3 polyclonal antibody (Cat # PAB27010).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using ME3 polyclonal antibody (Cat # PAB27010). -
Gene Info — ME3
Entrez GeneID
10873Protein Accession#
Q16798Gene Name
ME3
Gene Alias
FLJ34862
Gene Description
malic enzyme 3, NADP(+)-dependent, mitochondrial
Omim ID
604626Gene Ontology
HyperlinkGene Summary
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
Other Designations
NADP-ME|malate dehydrogenase|malic enzyme, NADP+-dependent, mitochondrial|mitochondrial NADP(+)-dependent malic enzyme 3|pyruvic-malic carboxylase
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of terpenoids and steroids
- Carbon fixation in photosynthetic organisms
- Metabolic pathways
- Pyruvate metabolism
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Disease
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