VASP (phospho S157) polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from NIH/3T3 cells untreated or treated with forskolin (40uM 30 min) using VASP (phospho S157) polyclonal antibody (Cat # PAB25826).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human tonsil carcinoma tissue using VASP (phospho S157) polyclonal antibody (Cat # PAB25826).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of VASP.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S157 of human VASP.
Sequence
R-V-Sp-N-A
Host
Rabbit
Theoretical MW (kDa)
50
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from NIH/3T3 cells untreated or treated with forskolin (40uM 30 min) using VASP (phospho S157) polyclonal antibody (Cat # PAB25826).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human tonsil carcinoma tissue using VASP (phospho S157) polyclonal antibody (Cat # PAB25826). -
Gene Info — VASP
Entrez GeneID
7408Protein Accession#
P50552Gene Name
VASP
Gene Alias
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Gene Description
vasodilator-stimulated phosphoprotein
Omim ID
601703Gene Ontology
HyperlinkGene Summary
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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