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CDKN1C polyclonal antibody

  • Catalog # : PAB25634
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CDKN1C.
  • Immunogen:
  • A synthetic peptide corresponding to 17 amino acids at N-terminus of human CDKN1C.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 35
  • Reactivity:
  • Human
  • Specificity:
  • At least three isoforms of CDKN1C are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, CDKN1C often migrates at 57kDa in SDS-PAGE. CDKN1C antibody is predicted to not cross react with other CIP/KIP proteins.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of CDKN1C in 293 cell lysate with CDKN1C polyclonal antibody (Cat # PAB25634) at (1) 1 and (2) 2 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1028
  • Gene Name:
  • CDKN1C
  • Gene Alias:
  • BWCR,BWS,KIP2,WBS,p57
  • Gene Description:
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • Gene Summary:
  • The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011736,cyclin-dependent kinase inhibitor 1C
  • Gene Pathway
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