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ATF6B polyclonal antibody

  • Catalog # : PAB24894
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ATF6B.
  • Immunogen:
  • A synthetic peptide corresponding to ATF6B.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 76
  • Reactivity:
  • Human
  • Specificity:
  • ATF6B polyclonal antibody detects endogenous levels of ATF6B protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of COLO 205 cell lysate with ATF6B polyclonal antibody (Cat # PAB24894).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1388
  • Gene Name:
  • ATF6B
  • Gene Alias:
  • CREB-RP,CREBL1,FLJ10066,G13
  • Gene Description:
  • activating transcription factor 6 beta
  • Gene Summary:
  • The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Creb-related protein,OTTHUMP00000029433,cAMP responsive element binding protein-like 1,cyclic AMP-dependent transcription factor ATF-6 beta,protein G13
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