MAP2K1 (phospho S298) polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa (lane 1) and HepG2 (lane 2) cell lysate with MAP2K1 (phospho S298) polyclonal antibody (Cat # PAB24735) at 1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP2K1.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S298 of MAP2K1.
Host
Rabbit
Theoretical MW (kDa)
50
Reactivity
Human
Specificity
MAP2K1 (phospho S298) polyclonal antibody detects endogenous levels of MAP2K1 protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa (lane 1) and HepG2 (lane 2) cell lysate with MAP2K1 (phospho S298) polyclonal antibody (Cat # PAB24735) at 1:500 dilution. -
Gene Info — MAP2K1
Entrez GeneID
5604Gene Name
MAP2K1
Gene Alias
MAPKK1, MEK1, MKK1, PRKMK1
Gene Description
mitogen-activated protein kinase kinase 1
Omim ID
176872Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq
Other Designations
protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)
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Interactome
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Pathway
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Disease
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