Products

Western Blot

Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PPP4R4 polyclonal antibody (Cat # PAB23865) at 1:250-1:500 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human liver with PPP4R4 polyclonal antibody (Cat # PAB23865) shows strong cytoplasmic positivity in hepatocytes at 1:200-1:500 dilution.

Immunofluorescence

Immunofluorescent staining of human cell line U-2 OS with PPP4R4 polyclonal antibody (Cat # PAB23865) at 1-4 ug/mL dilution shows positivity in cytoplasm.

Entrez GeneID

57718

Protein Accession#

Q6NUP7

Gene Name

PPP4R4

Gene Alias

KIAA1622, PP4R4

Gene Description

protein phosphatase 4, regulatory subunit 4

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The function of this particular gene product has not been determined. Alternative splicing has been observed for this gene and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq

Other Designations

HEAT-like repeat-containing protein