Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with LSM4 polyclonal antibody (Cat # PAB23720) at 1:250-1:500 dilution.
Immunohistochemical staining of human lateral ventricle with LSM4 polyclonal antibody (Cat # PAB23720) shows strong cytoplasmic positivity, with a granular pattern in neuronal cells at 1:200-1:500 dilution.
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM
U6 snRNA-associated Sm-like protein,U6 snRNA-associated Sm-like protein 4