NLRP10 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with NLRP10 polyclonal antibody (Cat # PAB23622) shows strong cytoplasmic positivity in tubular cells.
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NLRP10.
Immunogen
Recombinant protein corresponding to amino acids of human NLRP10.
Sequence
RARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with NLRP10 polyclonal antibody (Cat # PAB23622) shows strong cytoplasmic positivity in tubular cells. -
Gene Info — NLRP10
Entrez GeneID
338322Protein Accession#
Q86W26Gene Name
NLRP10
Gene Alias
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Gene Description
NLR family, pyrin domain containing 10
Omim ID
609662Gene Ontology
HyperlinkGene Summary
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq
Other Designations
NACHT, leucine rich repeat and PYD containing 10|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com