NLRP10 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of NLRP10 in human brain tissue lysate with NLRP10 polyclonal antibody (Cat # PAB19307) at 1 ug/mL.
Immunohistochemistry
Immunohistochemical staining of human brain cells with NLRP10 polyclonal antibody (Cat # PAB19307) at 10 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP10.
Immunogen
A synthetic peptide corresponding to 14 amino acids near N-terminus of human NLRP10.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of NLRP10 in human brain tissue lysate with NLRP10 polyclonal antibody (Cat # PAB19307) at 1 ug/mL.Immunohistochemistry
Immunohistochemical staining of human brain cells with NLRP10 polyclonal antibody (Cat # PAB19307) at 10 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NLRP10
Entrez GeneID
338322Protein Accession#
NP_789791Gene Name
NLRP10
Gene Alias
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Gene Description
NLR family, pyrin domain containing 10
Omim ID
609662Gene Ontology
HyperlinkGene Summary
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq
Other Designations
NACHT, leucine rich repeat and PYD containing 10|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10
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Interactome
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Disease
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