RICS polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with RICS polyclonal antibody (Cat # PAB23276) shows strong cytoplasmic and membrane positivity in glandular cells at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RICS.
Immunogen
Recombinant protein corresponding to amino acids of human RICS.
Sequence
ERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with RICS polyclonal antibody (Cat # PAB23276) shows strong cytoplasmic and membrane positivity in glandular cells at 1:50-1:200 dilution. -
Gene Info — RICS
Entrez GeneID
9743Protein Accession#
A7KAX9Gene Name
RICS
Gene Alias
GC-GAP, GRIT, KIAA0712, MGC1892, p200RhoGAP, p250GAP
Gene Description
Rho GTPase-activating protein
Omim ID
608541Gene Ontology
HyperlinkGene Summary
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM
Other Designations
GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein
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Interactome
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Disease
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