PIAS4 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
The PIAS4 polyclonal antibody (Cat # PAB2257) is used in Western blot to detect PIAS4 in HL-60 cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the PIAS4 polyclonal antibody (Cat # PAB2257) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PIAS4.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIAS4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
The PIAS4 polyclonal antibody (Cat # PAB2257) is used in Western blot to detect PIAS4 in HL-60 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the PIAS4 polyclonal antibody (Cat # PAB2257) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. -
Gene Info — PIAS4
Entrez GeneID
51588Protein Accession#
NP_056981;Q8N2W9Gene Name
PIAS4
Gene Alias
FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6
Gene Description
protein inhibitor of activated STAT, 4
Omim ID
605989Gene Ontology
HyperlinkGene Summary
O
Other Designations
protein inhibitor of activated STAT protein PIASy|zinc finger, MIZ-type containing 6
-
Interactome
-
Pathway
-
Publication Reference
-
The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.
Albor A, El-Hizawi S, Horn EJ, Laederich M, Frosk P, Wrogemann K, Kulesz-Martin M.
The Journal of Biological Chemistry 2006 Jun; 281(35):25850.
-
The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com