PIAS4 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of PIAS4 in (A) human liver, (B) mouse liver, (C) rat liver and (D) human Jurkat lysate using PIAS4 polyclonal antibody (Cat # PAB0167) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PIAS4.
Immunogen
A mixture of synthetic peptides corresponding to amino acids 46-60 and 187-198 of human PIAS4.
Sequence
KKIKELYETRYAKKNC, YSDTSCPQEDQY
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of PIAS4 in (A) human liver, (B) mouse liver, (C) rat liver and (D) human Jurkat lysate using PIAS4 polyclonal antibody (Cat # PAB0167) at 5 ug/mL .Immunocytochemistry
Immunofluorescence
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Gene Info — PIAS4
Entrez GeneID
51588Gene Name
PIAS4
Gene Alias
FLJ12419, MGC35296, PIASY, Piasg, ZMIZ6
Gene Description
protein inhibitor of activated STAT, 4
Omim ID
605989Gene Ontology
HyperlinkGene Summary
O
Other Designations
protein inhibitor of activated STAT protein PIASy|zinc finger, MIZ-type containing 6
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Interactome
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Pathway
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Publication Reference
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MUC1 expression is repressed by protein inhibitor of activated signal transducer and activator of transcription-y.
Brayman MJ, Dharmaraj N, Lagow E, Carson DD.
Molecular Endocrinology 2007 Aug; 21(11):2725.
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SUMO-1 modification of PIASy, an E3 ligase, is necessary for PIASy-dependent activation of Tcf-4.
Ihara M, Yamamoto H, Kikuchi A.
Molecular and Cellular Biology 2005 May; 25(9):3506.
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Convergence of interferon-gamma and progesterone signaling pathways in human endometrium: role of PIASy (protein inhibitor of activated signal transducer and activator of transcription-y).
Zoumpoulidou G, Jones MC, Fernandez de Mattos S, Francis JM, Fusi L, Lee YS, Christian M, Varshochi R, Lam EW, Brosens JJ.
Molecular Endocrinology 2004 May; 18(8):1988.
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MUC1 expression is repressed by protein inhibitor of activated signal transducer and activator of transcription-y.
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