DSCR3 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant DSCR3.
Immunogen
Recombinant protein corresponding to amino acids of human DSCR3.
Sequence
GKFPSGKTEIPFEFPLHLKGNKVLYETYHGVFVNIQYTLRCDMKRSLLAKDLTKTCEFIVHSAPQKGKFTPSPV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with DSCR3 polyclonal antibody (Cat # PAB21553) shows strong cytoplasmic positivity in granular pattern in glandular cells. -
Gene Info — DSCR3
Entrez GeneID
10311Protein Accession#
O14972Gene Name
DSCR3
Gene Alias
DCRA, DSCRA, MGC117385
Gene Description
Down syndrome critical region gene 3
Omim ID
605298Gene Ontology
HyperlinkGene Summary
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq
Other Designations
Down syndrome critical region protein 3|Down syndrome critical region protein A
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