DSCR4 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with DSCR4 polyclonal antibody (Cat # PAB21167).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with DSCR4 polyclonal antibody (Cat # PAB21167) shows strong cytoplasmic positivity in pancreatic duct cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DSCR4.
Immunogen
Recombinant protein corresponding to amino acids of human DSCR4.
Sequence
MSLIILTRDDEPRIFTPDSDAASPALHSTSPLPDPASASPLHREEKILPKVCNIVSCLSFSLPASPTDSGLASPTIITREGQQFWAKCLIWKYQLYLHGLHKKSDGR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with DSCR4 polyclonal antibody (Cat # PAB21167).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with DSCR4 polyclonal antibody (Cat # PAB21167) shows strong cytoplasmic positivity in pancreatic duct cells. -
Gene Info — DSCR4
Entrez GeneID
10281Protein Accession#
P56555Gene Name
DSCR4
Gene Alias
DCRB, DSCRB
Gene Description
Down syndrome critical region gene 4
Omim ID
604829Gene Ontology
HyperlinkGene Summary
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta. [provided by RefSeq
Other Designations
Down syndrome critical region protein 4|Down syndrome critical region protein B
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Interactome
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