Western blot analysis of PBK (arrow) using PBK polyclonal antibody (Cat # PAB2035). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PBK gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human testis tissue reacted with PBK polyclonal antibody (Cat # PAB2035) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. [provided by RefSeq
MAPKK-like protein kinase,PDZ-binding kinase,T-LAK cell-originated protein kinase,serine/threonine protein kinase,spermatogenesis-related protein kinase