DSG2 polyclonal antibody

Catalog # PAB20290

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Price

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Quantity

Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human prostate with DSG2 polyclonal antibody (Cat # PAB20290) shows strong membranous positivity in glandular cells at 1:50-1:200 dilution.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescent staining of human cell line A-431 with DSG2 polyclonal antibody (Cat # PAB20290) at 1-4 ug/mL dilution shows positivity in plasma membrane.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant DSG2.

    Immunogen

    Recombinant protein corresponding to amino acids of human DSG2.

    Sequence

    APPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNAS

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human prostate with DSG2 polyclonal antibody (Cat # PAB20290) shows strong membranous positivity in glandular cells at 1:50-1:200 dilution.

    Immunofluorescence

    Immunofluorescent staining of human cell line A-431 with DSG2 polyclonal antibody (Cat # PAB20290) at 1-4 ug/mL dilution shows positivity in plasma membrane.
  • Gene Info — DSG2

    Entrez GeneID

    1829

    Protein Accession#

    Q14126

    Gene Name

    DSG2

    Gene Alias

    ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037

    Gene Description

    desmoglein 2

    Omim ID

    125671 610193

    Gene Ontology

    Hyperlink

    Gene Summary

    Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq

    Other Designations

    HDGC

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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