Assay by immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified Myeloperoxidase [Human Leukocytes].?Cross reactivity against Myeloperoxidase from other tissues and species may occur but have not been specifically determined.
ELISA (1:5000-1:20000) WB (1:500-1:5000) IP (1:100) The optimal working dilution should be determined by the end user.
Lyophilized from 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% gentamicin sulfate)
Store at 4°C on dry atmosphere. After reconstitution with 0.1 mL of deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq