NLRP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human NLRP2 with DYKDDDDK tag probed with NLRP2 polyclonal antibody (Cat # PAB19696) (1 ug/mL) in lane 1 and probed with anti- DYKDDDDK Tag (1/1000) in lane 3. Mock-transfected HEK293 probed with NLRP2 polyclonal antibody (Cat # PAB19696) (1 mg/mL) in lane 2. Primary incubations were for 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NLRP2.
Immunogen
A synthetic peptide corresponding to C-terminus of human NLRP2.
Sequence
C-TEKHHPWAERPSSHD
Host
Goat
Theoretical MW (kDa)
150
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human NLRP2 with DYKDDDDK tag probed with NLRP2 polyclonal antibody (Cat # PAB19696) (1 ug/mL) in lane 1 and probed with anti- DYKDDDDK Tag (1/1000) in lane 3. Mock-transfected HEK293 probed with NLRP2 polyclonal antibody (Cat # PAB19696) (1 mg/mL) in lane 2. Primary incubations were for 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NLRP2
Entrez GeneID
55655Protein Accession#
NP_060322.1Gene Name
NLRP2
Gene Alias
CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
Gene Description
NLR family, pyrin domain containing 2
Omim ID
609364Gene Ontology
HyperlinkGene Summary
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
Other Designations
NACHT, LRR and PYD containing protein 2|NACHT, leucine rich repeat and PYD containing 2|PYRIN-Containing APAF1-like|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
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Interactome
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Disease
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