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Last updated: 2017/1/15

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NLRP2 polyclonal antibody

  • Catalog # : PAB19696
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of NLRP2.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human NLRP2.
  • Sequence:
  • C-TEKHHPWAERPSSHD
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 150
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human NLRP2 with DYKDDDDK tag probed with NLRP2 polyclonal antibody (Cat # PAB19696) (1 ug/mL) in lane 1 and probed with anti- DYKDDDDK Tag (1/1000) in lane 3. Mock-transfected HEK293 probed with NLRP2 polyclonal antibody (Cat # PAB19696) (1 mg/mL) in lane 2. Primary incubations were for 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • NLRP2
  • Gene Alias:
  • CLR19.9,FLJ20510,NALP2,NBS1,PAN1,PYPAF2
  • Gene Description:
  • NLR family, pyrin domain containing 2
  • Gene Summary:
  • NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
  • Other Designations:
  • NACHT, LRR and PYD containing protein 2,NACHT, leucine rich repeat and PYD containing 2,PYRIN-Containing APAF1-like,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
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